Thesis: Automation of Drug Target Profiling for Logical Modelling (2023)

The aim of my master’s project is to contribute to automate drug target profile annotation for the DrugLogic pipeline. The first objective is to produce an inventory of available public and in-house data sets from drug screens, providing an organised catalogue of cancer drugs and their molecular target profiles. The next objective is to use identified target profiles in logical modelling to predict and analyse drug responses, considering also off-targets effects that can cause a toxic response.